White or milky white crystalline powder. Melting point 158-160, soluble in hot water, slightly soluble in ethanol, slightly soluble in water, very slightly soluble in ether. Bitter and slightly salty taste.
Melting point. |
159-161°C(lit.) |
Boiling point. |
301.12°C(roughestimate) |
Density. |
1.3994(roughestimate) |
Refractive index. |
1.5800 (estimate) |
Storage |
2-8°C |
Metronidazole is a nitroimidazole antibiotic, kills anaerobic microorganisms, and the metabolites it generates when it is reduced in the human body also have an anaerobic effect, inhibiting bacterial DNA synthesis, thus interfering with bacterial growth, reproduction, and ultimately bacterial death, anti-anaerobic bacterial Pu including: anaerobic bacterial bacteria fragile mimic bacillus, clostridium difficile (due to the Clostridium fragilis, Clostridium perfringens (so named because of the shape of the bacterium's body is sharp at both ends), Tetanus bacillus, Digestive Coccus, Digestive Streptococcus, and JaChemicalbook Flagellates.
It was initially used for the treatment of vaginal trichomoniasis with very significant clinical results. It was later discovered that metronidazole could also kill the anaerobic bacteria that cause oral infections.